
Vitamin D is often called the “sunshine vitamin,” but its importance extends far beyond what most people realize. This complete guide to vitamin D will reveal how this essential nutrient acts more like a hormone in your body, influencing everything from bone health and immune function to mood regulation and cardiovascular health. Despite its critical role, vitamin D deficiency has become incredibly common, affecting an estimated 1 billion people worldwide.
Where Do We Get Vitamin D?
Sun Exposure: Nature’s Primary Source
Your skin produces vitamin D when exposed to UVB radiation from sunlight. This process begins when 7-dehydrocholesterol in your skin converts to previtamin D3, which then transforms into vitamin D3 (cholecalciferol). However, several factors affect this natural production:
Optimal sun exposure guidelines:
- Aim for 10-30 minutes of midday sun exposure several times per week
- Fair-skinned individuals need less time; darker skin requires longer exposure
- The amount of skin exposed matters – more exposed skin means more vitamin D production
- Geographic location and season significantly impact UVB availability
Factors that reduce sun-derived vitamin D:
- Sunscreen (SPF 8 or higher blocks 95% of vitamin D production)
- Cloud cover and air pollution
- Glass windows (block UVB rays)
- Geographic latitude (more on this below)
- Time of day (UVB is strongest between 10 AM and 2 PM)
Dietary Sources: Limited but Important
Unfortunately, very few foods naturally contain significant amounts of vitamin D:
Natural food sources:
- Fatty fish (salmon, mackerel, sardines, tuna): 400-1000 IU per 3.5 oz serving
- Cod liver oil: 1360 IU per tablespoon
- Egg yolks from pasture-raised chickens: 20-40 IU per yolk
- Mushrooms exposed to UV light: Variable amounts
- Beef liver: Small amounts (about 40 IU per 3.5 oz)
Supplements: Bridging the Gap
Given the limited dietary sources and challenges with sun exposure, supplementation often becomes necessary for maintaining optimal vitamin D levels.
Vitamin D2 vs D3: Which Should You Choose?
There are two main forms of vitamin D supplements:
Vitamin D2 (Ergocalciferol):
- Derived from plants and fungi
- Less effective at raising blood levels of 25(OH)D
- Shorter duration of action
- Often used in prescription medications
Vitamin D3 (Cholecalciferol):
- Derived from animal sources (traditionally sheep’s wool)
- More effective at raising and maintaining blood levels
- Longer-lasting in the body
- Preferred form for supplementation
- Better absorbed and utilized by the body
For vegans: Plant-based D3 supplements are now available, derived from lichen, making them suitable for those following plant-based diets.
Absorption and Bioavailability
Vitamin D is a fat-soluble vitamin, which means it requires dietary fat for optimal absorption. Here’s how to maximize absorption:
Take with fat: Consume vitamin D supplements with a meal containing healthy fats like avocado, nuts, olive oil, or fatty fish. This can increase absorption by up to 50%.
Timing matters: Some research suggests taking vitamin D with your largest meal of the day for better absorption.
Individual factors: Gut health, age, and certain medications can all impact absorption rates.
Essential Co-factors for Vitamin D Function
Vitamin D doesn’t work alone. Several nutrients are crucial for its proper metabolism and function:
Magnesium: The Critical Partner
Magnesium is required for vitamin D metabolism and activation. Without adequate magnesium, vitamin D remains largely inactive in your body. Many people are deficient in magnesium, which can explain why some individuals don’t respond well to vitamin D supplementation alone.
Recommended approach: Ensure adequate magnesium intake (300-400mg daily for most adults) through foods like leafy greens, nuts, seeds, and whole grains, or consider supplementation.
Vitamin K2: Directing Calcium
Vitamin K2 works synergistically with vitamin D to ensure calcium is deposited in bones and teeth rather than soft tissues like arteries. This is crucial for both bone health and cardiovascular protection.
Sources: Fermented foods (sauerkraut) and egg yolks
Other Important Co-factors
- Vitamin A: Works with vitamin D for immune function and bone health
- Zinc: Supports vitamin D receptor function
- Boron: Enhances vitamin D metabolism
Causes of Low Vitamin D
Understanding why vitamin D deficiency is so common helps explain why supplementation is often necessary:
Geographic and Environmental Factors
Northern latitudes: If you live above the 37th parallel (roughly the latitude of San Francisco), you likely can’t produce adequate vitamin D from sun exposure during winter months. The “vitamin D winter” can last 4-6 months in northern climates.
Indoor lifestyle: Modern life keeps many people indoors during peak UVB hours, significantly reducing natural vitamin D production.
Air pollution: Urban environments with high pollution levels can block UVB rays, reducing vitamin D synthesis.
Individual Risk Factors
Age: Older adults have reduced capacity to synthesize vitamin D through their skin and may have decreased dietary absorption.
Skin pigmentation: Melanin acts as a natural sunscreen, so individuals with darker skin require longer sun exposure to produce the same amount of vitamin D as those with lighter skin.
Body weight: Vitamin D is fat-soluble and can become sequestered in adipose tissue, making it less available for use in individuals with higher body fat percentages.
Gut health issues: Conditions like celiac disease, Crohn’s disease, ulcerative colitis, and other digestive disorders can impair vitamin D absorption.
Medications That Interfere
Several medications can affect vitamin D metabolism:
- Corticosteroids (prednisone)
- Weight loss medications (orlistat)
- Cholesterol-lowering drugs (cholestyramine)
- Anti-seizure medications (phenytoin, phenobarbital)
- Some antibiotics

Recognizing Vitamin D Deficiency
Vitamin D deficiency can be subtle, but common signs and symptoms include:
Physical symptoms:
- Fatigue and weakness
- Bone and muscle pain
- Frequent infections or slow healing
- Depression or mood changes
- Hair loss
- Muscle weakness or cramps
Long-term health risks:
- Increased risk of osteoporosis and fractures
- Compromised immune function
- Higher risk of respiratory infections
- Potential increased risk of autoimmune conditions
- Cardiovascular health concerns
Testing Your Vitamin D Status
The most accurate way to assess your vitamin D status is through a blood test measuring 25-hydroxyvitamin D [25(OH)D], also called calcidiol. This is the storage form of vitamin D and the best indicator of your body’s vitamin D status.
Optimal blood levels:
- Deficient: Less than 20 ng/mL (50 nmol/L)
- Insufficient: 20-29 ng/mL (50-74 nmol/L)
- Sufficient: 30-100 ng/mL (75-250 nmol/L)
- Optimal for health: 40-60 ng/mL (100-150 nmol/L)
Testing options: Home finger-prick tests are now available, making it convenient to monitor your vitamin D status regularly. These tests are accurate and allow you to track your levels over time.
How to Boost Your Vitamin D Levels
Supplementation Guidelines
Starting doses: For most adults with deficiency, 2000-4000 IU daily is often needed to achieve optimal levels. Some individuals may require higher doses initially.
Maintenance doses: Once optimal levels are achieved, 1000-2000 IU daily typically maintains adequate status.
High-dose protocols: For severe deficiency, some practitioners recommend higher doses (5000-10,000 IU daily) for a limited period, always under professional guidance.
Maximizing Food Sources
While supplementation is often necessary, including vitamin D-rich foods in your diet provides additional benefits:
Weekly meal planning ideas:
- Include fatty fish 2-3 times per week
- Choose pasture-raised eggs when possible
Lifestyle Optimization
Safe sun exposure:
- Spend time outdoors during midday hours when possible
- Expose arms, legs, or back without sunscreen for short periods
- Balance sun exposure with skin cancer prevention
Supporting overall health:
- Maintain a healthy weight
- Address gut health issues
- Manage stress, which can affect nutrient absorption
- Ensure adequate sleep for hormone regulation

When to Retest
Regular monitoring ensures your vitamin D optimization strategy is working:
Initial testing schedule:
- Test baseline levels before starting supplementation
- Retest after 8-12 weeks of consistent supplementation
- Adjust dosing based on results
Maintenance testing:
- Test every 3-6 months initially
- Once stable, annual testing may be sufficient
- Consider more frequent testing if you have risk factors or health conditions
Seasonal considerations: If you rely on sun exposure, consider testing at the end of summer and end of winter to see seasonal variations.
The Bottom Line
Vitamin D is a critical nutrient that affects virtually every system in your body. While our ancestors likely maintained adequate levels through sun exposure and dietary sources, modern lifestyle factors make deficiency incredibly common. The good news is that with proper testing, supplementation, and lifestyle modifications, achieving optimal vitamin D status is entirely achievable.
Remember that vitamin D optimization is not a one-size-fits-all approach. Factors like your geographic location, lifestyle, health status, and individual biochemistry all influence your needs. Working with a knowledgeable healthcare practitioner can help you develop a personalized strategy for achieving and maintaining optimal vitamin D levels.
Ready to Optimize Your Health with Personalized Functional Medicine?
If you’re ready to take a deeper dive into your health and discover how vitamin D optimization fits into your unique wellness picture, We’d love to help. Every person’s nutritional needs are different, and what works for one individual may not be the right approach for another.
Schedule your complimentary 15-minute functional medicine consultation here where we’ll discuss:
- Your current symptoms and health goals
- How vitamin D testing and optimization could benefit you specifically
- Which co-factors and supportive nutrients might be most important for your situation
- A personalized approach to addressing the root causes of your health concerns